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Exosome-Mediated Delivery of the Neuroprotective Peptide PACAP38 Promotes Retinal Ganglion Cell Survival and Axon Regeneration in Rats With Traumatic Optic Neuropathy
Traumatic optic neuropathy (TON) refers to optic nerve damage caused by trauma, leading to partial or complete loss of vision. The primary treatment options, such as hormonal therapy and surgery, have limited efficacy. Pituitary adenylate cyclase-activating polypeptide 38 (PACAP38), a functional end...
Autores principales: | Wang, Tian, Li, Yiming, Guo, Miao, Dong, Xue, Liao, Mengyu, Du, Mei, Wang, Xiaohong, Yin, Haifang, Yan, Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055942/ https://www.ncbi.nlm.nih.gov/pubmed/33889576 http://dx.doi.org/10.3389/fcell.2021.659783 |
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