Sulfatase 2-Induced Cancer-Associated Fibroblasts Promote Hepatocellular Carcinoma Progression via Inhibition of Apoptosis and Induction of Epithelial-to-Mesenchymal Transition

BACKGROUND: Sulfatase 2 (SULF2) removes the 6-O-sulfate groups from heparan sulfate proteoglycans (HSPG) and consequently alters the binding sites for various signaling molecules. Here, we elucidated the role of SULF2 in the differentiation of hepatic stellate cells (HSCs) into carcinoma-associated...

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Detalles Bibliográficos
Autores principales: Wang, Cong, Shang, Chuzhi, Gai, Xiaohong, Song, Tao, Han, Shaoshan, Liu, Qingguang, Zheng, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056031/
https://www.ncbi.nlm.nih.gov/pubmed/33889573
http://dx.doi.org/10.3389/fcell.2021.631931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056031/
https://www.ncbi.nlm.nih.gov/pubmed/33889573
http://dx.doi.org/10.3389/fcell.2021.631931

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