Cargando…

Sulfatase 2-Induced Cancer-Associated Fibroblasts Promote Hepatocellular Carcinoma Progression via Inhibition of Apoptosis and Induction of Epithelial-to-Mesenchymal Transition

BACKGROUND: Sulfatase 2 (SULF2) removes the 6-O-sulfate groups from heparan sulfate proteoglycans (HSPG) and consequently alters the binding sites for various signaling molecules. Here, we elucidated the role of SULF2 in the differentiation of hepatic stellate cells (HSCs) into carcinoma-associated...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Cong, Shang, Chuzhi, Gai, Xiaohong, Song, Tao, Han, Shaoshan, Liu, Qingguang, Zheng, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056031/ https://www.ncbi.nlm.nih.gov/pubmed/33889573 http://dx.doi.org/10.3389/fcell.2021.631931

Ejemplares similares

Stepwise Induction of Inner Ear Hair Cells From Mouse Embryonic Fibroblasts via Mesenchymal- to-Epithelial Transition and Formation of Otic Epithelial Cells
por: Yang, Qiong, et al.
Publicado: (2021)

Cortactin in Epithelial–Mesenchymal Transition
por: Ji, Rong, et al.
Publicado: (2020)

Induction of Autophagy by Pterostilbene Contributes to the Prevention of Renal Fibrosis via Attenuating NLRP3 Inflammasome Activation and Epithelial-Mesenchymal Transition
por: Wang, Ying-Jan, et al.
Publicado: (2020)

Mechanochemical Signaling of the Extracellular Matrix in Epithelial-Mesenchymal Transition
por: Scott, Lewis E., et al.
Publicado: (2019)

Epithelial–mesenchymal transition: an organizing principle of mammalian regeneration
por: Bedelbaeva, Kamila, et al.
Publicado: (2023)

Circular RNA hsa_circ_0004277 Stimulates Malignant Phenotype of Hepatocellular Carcinoma and Epithelial-Mesenchymal Transition of Peripheral Cells
por: Zhu, Chuanrong, et al.
Publicado: (2021)

Unexpected Phenotype Reversion and Survival in a Zebrafish Model of Multiple Sulfatase Deficiency
por: Fleming, Angeleen, et al.
Publicado: (2022)

Exploring the Metabolic Vulnerabilities of Epithelial–Mesenchymal Transition in Breast Cancer
por: Sun, Xiangyu, et al.
Publicado: (2020)

Role of Epithelial-Mesenchymal Transition in Retinal Pigment Epithelium Dysfunction
por: Zhou, Mi, et al.
Publicado: (2020)

The Epithelial-to-Mesenchymal Transition as a Possible Therapeutic Target in Fibrotic Disorders
por: Di Gregorio, Jacopo, et al.
Publicado: (2020)

Epithelial-Mesenchymal Transition Induces GSDME Transcriptional Activation for Inflammatory Pyroptosis
por: Jia, Chenqiang, et al.
Publicado: (2021)

Role of the epithelial barrier in intestinal fibrosis associated with inflammatory bowel disease: relevance of the epithelial-to mesenchymal transition
por: Macias-Ceja, Dulce C., et al.
Publicado: (2023)

Epithelial-Mesenchymal Transition Drives Three-Dimensional Morphogenesis in Mammalian Early Development
por: Ismagulov, Galym, et al.
Publicado: (2021)

Vitamin D Enhances Radiosensitivity of Colorectal Cancer by Reversing Epithelial-Mesenchymal Transition
por: Yu, Xinyue, et al.
Publicado: (2021)

Effect of ISM1 on the Immune Microenvironment and Epithelial-Mesenchymal Transition in Colorectal Cancer
por: Wu, Yuhui, et al.
Publicado: (2021)

Surface tension of model tissues during malignant transformation and epithelial–mesenchymal transition
por: Nagle, Irène, et al.
Publicado: (2022)

Expression of R345W-Fibulin-3 Induces Epithelial-Mesenchymal Transition in Retinal Pigment Epithelial Cells
por: Zhou, Mi, et al.
Publicado: (2020)

Epithelial-Mesenchymal Transition and Metabolic Switching in Cancer: Lessons From Somatic Cell Reprogramming
por: Lai, Xiaowei, et al.
Publicado: (2020)

Mechanistic Insights Delineating the Role of Cholesterol in Epithelial Mesenchymal Transition and Drug Resistance in Cancer
por: Abdulla, Naaziyah, et al.
Publicado: (2021)

Lens Fibrosis: Understanding the Dynamics of Cell Adhesion Signaling in Lens Epithelial-Mesenchymal Transition
por: Taiyab, Aftab, et al.
Publicado: (2022)

CircFGGY Inhibits Cell Growth, Invasion and Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma via Regulating the miR-545-3p/Smad7 Axis
por: Feng, Kun-Liang, et al.
Publicado: (2022)

Overexpression of NREP Promotes Migration and Invasion in Gastric Cancer Through Facilitating Epithelial-Mesenchymal Transition
por: Liu, Yuan-jie, et al.
Publicado: (2021)

Identification of Epithelial–Mesenchymal Transition-Related Prognostic lncRNAs Biomarkers Associated With Melanoma Microenvironment
por: Xiao, Bo, et al.
Publicado: (2021)

Pyruvate Dehydrogenase Contributes to Drug Resistance of Lung Cancer Cells Through Epithelial Mesenchymal Transition
por: Cevatemre, Buse, et al.
Publicado: (2022)

Steroid sulfatase promotes invasion through epithelial-mesenchymal transition and predicts the progression of bladder cancer
por: Shimizu, Yasuomi, et al.
Publicado: (2018)

Transient Receptor Potential Channel 6 Knockout Ameliorates Kidney Fibrosis by Inhibition of Epithelial–Mesenchymal Transition
por: Zhang, Yanhong, et al.
Publicado: (2021)

An emerging role of the cellular prion protein as a modulator of a morphogenetic program underlying epithelial-to-mesenchymal transition
por: Mehrabian, Mohadeseh, et al.
Publicado: (2014)

Activin A and ALK4 Identified as Novel Regulators of Epithelial to Mesenchymal Transition (EMT) in Human Epicardial Cells
por: Dronkers, Esther, et al.
Publicado: (2021)

PDE4B Induces Epithelial-to-Mesenchymal Transition in Bladder Cancer Cells and Is Transcriptionally Suppressed by CBX7
por: Huang, Zhengnan, et al.
Publicado: (2021)

Endothelial-to-Mesenchymal Transition in Cancer
por: Clere, Nicolas, et al.
Publicado: (2020)

Calcium Binding Protein S100A16 Expedites Proliferation, Invasion and Epithelial-Mesenchymal Transition Process in Gastric Cancer
por: You, Xiaoying, et al.
Publicado: (2021)

Mesenchymal Epithelial Transition Factor Signaling in Pediatric Nervous System Tumors: Implications for Malignancy and Cancer Stem Cell Enrichment
por: Khater, Amanda Rose, et al.
Publicado: (2021)

MiR-4319 induced an inhibition of epithelial-mesenchymal transition and prevented cancer stemness of HCC through targeting FOXQ1
por: Han, Shaoshan, et al.
Publicado: (2019)

Downregulated lncRNA GAS5 and Upregulated miR-21 Lead to Epithelial–Mesenchymal Transition and Lung Metastasis of Osteosarcomas
por: Wang, Ying, et al.
Publicado: (2021)

Cross-Talk Between Tumor Cells Undergoing Epithelial to Mesenchymal Transition and Natural Killer Cells in Tumor Microenvironment in Colorectal Cancer
por: Vuletić, Ana, et al.
Publicado: (2021)

PSMC5 Promotes Proliferation and Metastasis of Colorectal Cancer by Activating Epithelial–Mesenchymal Transition Signaling and Modulating Immune Infiltrating Cells
por: He, Zirui, et al.
Publicado: (2021)

Sulfatase-2 from Cancer Associated Fibroblasts: An Environmental Target for Hepatocellular Carcinoma?
por: Zaki, Marco Y.W., et al.
Publicado: (2022)

Pentraxin 3 overexpression accelerated tumor metastasis and indicated poor prognosis in hepatocellular carcinoma via driving epithelial-mesenchymal transition
por: Song, Tao, et al.
Publicado: (2018)

Editorial: Epithelial to Mesenchymal Plasticity in Colorectal Cancer
por: Bocci, Federico, et al.
Publicado: (2022)

A KDM4-DBC1-SIRT1 Axis Contributes to TGF-b Induced Mesenchymal Transition of Intestinal Epithelial Cells
por: Chen, Baoyu, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_dkrn4iaaa2vigtede60kdqm5pu