Double-Controlled Release of Poorly Water-Soluble Paliperidone Palmitate from Self-Assembled Albumin-Oleic Acid Nanoparticles in PLGA in situ Forming Implant

PURPOSE: To investigate the effects of solvents on the formation of self-assembled nanonization of albumin-oleic acid conjugates (AOCs) using a solvent exchange mechanism for the construction of in situ forming implants (ISFI). METHODS: A poorly water-soluble drug, paliperidone palmitate (PPP), was...

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Detalles Bibliográficos
Autores principales: Yu, Yongjun, Ngo, Hai V, Jin, Gang, Tran, Phuong H L, Tran, Thao T D, Nguyen, Van Hong, Park, Chulhun, Lee, Beom-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056066/
https://www.ncbi.nlm.nih.gov/pubmed/33888982
http://dx.doi.org/10.2147/IJN.S302514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056066/
https://www.ncbi.nlm.nih.gov/pubmed/33888982
http://dx.doi.org/10.2147/IJN.S302514

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