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Slc20a2-Deficient Mice Exhibit Multisystem Abnormalities and Impaired Spatial Learning Memory and Sensorimotor Gating but Normal Motor Coordination Abilities

BACKGROUND: Primary familial brain calcification (PFBC, OMIM#213600), also known as Fahr’s disease, is a rare autosomal dominant or recessive neurodegenerative disorder characterized by bilateral and symmetrical microvascular calcifications affecting multiple brain regions, particularly the basal ga...

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Detalles Bibliográficos
Autores principales: Ren, Yaqiong, Shen, Yuqi, Si, Nuo, Fan, Shiqi, Zhang, Yi, Xu, Wanhai, Shi, Lei, Zhang, Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056086/
https://www.ncbi.nlm.nih.gov/pubmed/33889180
http://dx.doi.org/10.3389/fgene.2021.639935