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DNA-binding function of c-Myb R2R3 around thermal denaturation temperature

The minimum DNA-binding domain of the transcrip­tional factor c-Myb R2R3 remarkably fluctuates in the solution. In the present study, we evaluated the protein fluctuation of R2R3 C130I mutant, R2R3*, on its DNA-binding and folding thermodynamics. DNA-binding analysis using isothermal titration calor...

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Detalles Bibliográficos
Autores principales: Kawasaki, Maki, Oda, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society of Japan 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056152/
https://www.ncbi.nlm.nih.gov/pubmed/33977005
http://dx.doi.org/10.2142/biophysico.bppb-v18.009