In-line monitoring of surfactant clearance in viral vaccine downstream processing

PURPOSE: The goal of this study is to examine the suitability of in-line infrared measurements to monitor, in real-time, surfactant concentration in the viral vaccine drug substance during a 50KDa tangential flow filtration (TFF) process. METHODS: A ReactIR™ 702L instrument was used to gather spectr...

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Detalles Bibliográficos
Autores principales: Payne, Jessie, Cronin, James, Haer, Manjit, Krouse, Jason, Prosperi, William, Drolet-Vives, Katherine, Lieve, Matthew, Soika, Michael, Balmer, Matthew, Kirkitadze, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056174/
https://www.ncbi.nlm.nih.gov/pubmed/33897983
http://dx.doi.org/10.1016/j.csbj.2021.03.030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056174/
https://www.ncbi.nlm.nih.gov/pubmed/33897983
http://dx.doi.org/10.1016/j.csbj.2021.03.030

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