CDK7 Inhibitor THZ1 Induces the Cell Apoptosis of B-Cell Acute Lymphocytic Leukemia by Perturbing Cellular Metabolism

B-cell acute lymphocytic leukemia (B-ALL) is a malignant blood cancer that develops in children and adults and leads to high mortality. THZ1, a covalent cyclin-dependent kinase 7 (CDK7) inhibitor, shows anti-tumor effects in various cancers by inhibiting cell proliferation and inducing apoptosis. Ho...

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Detalles Bibliográficos
Autores principales: Abudureheman, Tuersunayi, Xia, Jing, Li, Ming-Hao, Zhou, Hang, Zheng, Wei-Wei, Zhou, Neng, Shi, Rong-Yi, Zhu, Jian-Min, Yang, Li-Ting, Chen, Li, Zheng, Liang, Xue, Kai, Qing, Kai, Duan, Cai-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056175/
https://www.ncbi.nlm.nih.gov/pubmed/33889549
http://dx.doi.org/10.3389/fonc.2021.663360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056175/
https://www.ncbi.nlm.nih.gov/pubmed/33889549
http://dx.doi.org/10.3389/fonc.2021.663360

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