Efficient lentiviral transduction method to gene modify cord blood CD8(+) T cells for cancer therapy applications

Adoptive T cell therapy utilizing tumor-specific autologous T cells has shown promising results for cancer treatment. However, the limited numbers of autologous tumor-associated antigen (TAA)-specific T cells and the functional aberrancies, due to disease progression or treatment, remain factors tha...

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Detalles Bibliográficos
Autores principales: Lo Presti, Vania, Cornel, Annelisa M., Plantinga, Maud, Dünnebach, Ester, Kuball, Jurgen, Boelens, Jaap Jan, Nierkens, Stefan, van Til, Niek P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056177/
https://www.ncbi.nlm.nih.gov/pubmed/33898633
http://dx.doi.org/10.1016/j.omtm.2021.03.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056177/
https://www.ncbi.nlm.nih.gov/pubmed/33898633
http://dx.doi.org/10.1016/j.omtm.2021.03.015

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