Cargando…

Efficient lentiviral transduction method to gene modify cord blood CD8(+) T cells for cancer therapy applications

Adoptive T cell therapy utilizing tumor-specific autologous T cells has shown promising results for cancer treatment. However, the limited numbers of autologous tumor-associated antigen (TAA)-specific T cells and the functional aberrancies, due to disease progression or treatment, remain factors tha...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lo Presti, Vania, Cornel, Annelisa M., Plantinga, Maud, Dünnebach, Ester, Kuball, Jurgen, Boelens, Jaap Jan, Nierkens, Stefan, van Til, Niek P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056177/ https://www.ncbi.nlm.nih.gov/pubmed/33898633 http://dx.doi.org/10.1016/j.omtm.2021.03.015

Ejemplares similares

Clinical Grade Production of Wilms’ Tumor-1 Loaded Cord Blood-Derived Dendritic Cells to Prevent Relapse in Pediatric AML After Cord Blood Transplantation
por: Plantinga, Maud, et al.
Publicado: (2020)

Strategies to Genetically Modulate Dendritic Cells to Potentiate Anti-Tumor Responses in Hematologic Malignancies
por: Cornel, Annelisa M., et al.
Publicado: (2018)

Cord-Blood-Stem-Cell-Derived Conventional Dendritic Cells Specifically Originate from CD115-Expressing Precursors
por: Plantinga, Maud, et al.
Publicado: (2019)

A “No‐Touch” Antibody‐Staining Method of Adherent Cells for High‐Throughput Flow Cytometry in 384‐Well Microplate Format for Cell‐Based Drug Library Screening
por: Cornel, Annelisa M., et al.
Publicado: (2019)

CD14 Expressing Precursors Give Rise to Highly Functional Conventional Dendritic Cells for Use as Dendritic Cell Vaccine
por: Plantinga, Maud, et al.
Publicado: (2021)

Gene Augmentation and Editing to Improve TCR Engineered T Cell Therapy against Solid Tumors
por: Lo Presti, Vania, et al.
Publicado: (2020)

Development of a unique anti-AML immune therapy consisting of cord blood HSCT and cord blood stem cell-derived dendritic cell (CB-DC) vaccination
por: de Haar, Colin, et al.
Publicado: (2013)

Dendritic Cell Therapy in an Allogeneic-Hematopoietic Cell Transplantation Setting: An Effective Strategy toward Better Disease Control?
por: Plantinga, Maud, et al.
Publicado: (2014)

Reduction of liver macrophage transduction by pseudotyping lentiviral vectors with a fusion envelope from Autographa californica GP64 and Sendai virus F2 domain
por: Markusic, David M, et al.
Publicado: (2009)

Process for an efficient lentiviral cell transduction
por: Pirona, Anna Chiara, et al.
Publicado: (2020)

Lentiviral transduction of rat Sertoli cells as a means to modify gene expression
por: Nicholls, Peter K., et al.
Publicado: (2012)

MHC Class I Downregulation in Cancer: Underlying Mechanisms and Potential Targets for Cancer Immunotherapy
por: Cornel, Annelisa M., et al.
Publicado: (2020)

Driving DNA transposition by lentiviral protein transduction
por: Cai, Yujia, et al.
Publicado: (2014)

High-efficiency transduction of spinal cord motor neurons by intrauterine delivery of integration-deficient lentiviral vectors
por: Ahmed, Sherif G., et al.
Publicado: (2018)

Transduction of modified factor VIII gene improves lentiviral gene therapy efficacy for hemophilia A
por: Gong, Jie, et al.
Publicado: (2021)

Avoiding lentiviral transduction culture induced MSC senescence
por: Pan, Yung-Wei, et al.
Publicado: (2009)

Optimized protocols for γδ T cell expansion and lentiviral transduction
por: Wang, Rui-Ning, et al.
Publicado: (2019)

Lentiviral Transduction of CD34(+) Cells Induces Genome-Wide Epigenetic Modifications
por: Yamagata, Yoshiaki, et al.
Publicado: (2012)

Epigenetic modulation of neuroblastoma enhances T cell and NK cell immunogenicity by inducing a tumor-cell lineage switch
por: Cornel, Annelisa M, et al.
Publicado: (2022)

Population Pharmacokinetics of Fludarabine in Children and Adults during Conditioning Prior to Allogeneic Hematopoietic Cell Transplantation
por: Langenhorst, Jurgen B., et al.
Publicado: (2018)

Immune Monitoring during Therapy Reveals Activitory and Regulatory Immune Responses in High-Risk Neuroblastoma
por: Szanto, Celina L., et al.
Publicado: (2021)

Monitoring Immune Responses in Neuroblastoma Patients during Therapy
por: Szanto, Celina L., et al.
Publicado: (2020)

Minimal impact of ZAP on lentiviral vector production and transduction efficiency
por: Sertkaya, Helin, et al.
Publicado: (2021)

Identification of a small molecule for enhancing lentiviral transduction of T cells
por: Malach, Paulina, et al.
Publicado: (2023)

Decitabine Suspends Human CD34(+) Cell Differentiation and Proliferation during Lentiviral Transduction
por: Uchida, Naoya, et al.
Publicado: (2014)

CD9 and folate receptor overexpression are not sufficient for VSV-G-independent lentiviral transduction
por: Bellotti, Cristina, et al.
Publicado: (2022)

Engineering fusogenic molecules to achieve targeted transduction of enveloped lentiviral vectors
por: Lei, Yuning, et al.
Publicado: (2009)

Lentiviral vector transduction of spermatozoa as a tool for the study of early development
por: Chandrashekran, Anil, et al.
Publicado: (2014)

Toward Tightly Tuned Gene Expression Following Lentiviral Vector Transduction
por: Page, Audrey, et al.
Publicado: (2020)

Cellular Proteo-Transcriptomic Changes in the Immediate Early-Phase of Lentiviral Transduction
por: Linkner, Tamás Richárd, et al.
Publicado: (2021)

Lentiviral transduction facilitates RNA interference in the nematode parasite Nippostrongylus brasiliensis
por: Hagen, Jana, et al.
Publicado: (2021)

Immune Monitoring After Allogeneic Hematopoietic Cell Transplantation: Toward Practical Guidelines and Standardization
por: Boelens, Jaap Jan, et al.
Publicado: (2020)

P437: EFFECTIVE IMMUNOTHERAPY OF PEDIATRIC T(8;21) ACUTE MYELOID LEUKEMIA BY REPURPOSING CD3XCD19 TARGETING BISPECIFIC ANTIBODIES
por: Wijnen, Noa, et al.
Publicado: (2023)

Antitumor immune responses mediated by dendritic cells: How signals derived from dying cancer cells drive antigen cross-presentation
por: Spel, Lotte, et al.
Publicado: (2013)

A Nontoxic Transduction Enhancer Enables Highly Efficient Lentiviral Transduction of Primary Murine T Cells and Hematopoietic Stem Cells
por: Delville, Marianne, et al.
Publicado: (2018)

Alteration of T cell immunity by lentiviral transduction of human monocyte-derived dendritic cells
por: Chen, Xiaochuan, et al.
Publicado: (2004)

In situ transduction of stromal cells and thymocytes upon intrathymic injection of lentiviral vectors
por: Marodon, Gilles, et al.
Publicado: (2004)

Polybrene Inhibits Human Mesenchymal Stem Cell Proliferation during Lentiviral Transduction
por: Lin, Paul, et al.
Publicado: (2011)

Improving the Transduction of Bone Marrow–Derived Cells with an Integrase-Defective Lentiviral Vector
por: Pay, S. Louise, et al.
Publicado: (2018)

Proteasome Inhibition Increases the Efficiency of Lentiviral Vector-Mediated Transduction of Trabecular Meshwork
por: Aktas, Zeynep, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_9mg4sgk2jtuj4hhekhd00mau99