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Study the lipidoid nanoparticle mediated genome editing protein delivery using 3D intestinal tissue model

Lipid nanoparticles are promising carriers for oral drug delivery. For bioactive cargos with intracellular targets, e.g. gene-editing proteins, it is essential for the cargo and carrier to remain complexed after crossing the epithelial layer of intestine in order for the delivery system to transport...

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Detalles Bibliográficos
Autores principales: Yang, Tao, Han, Haobo, Chen, Ying, Yang, Liu, Parker, Rachael, Li, Yamin, Kaplan, David L., Xu, Qiaobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056182/
https://www.ncbi.nlm.nih.gov/pubmed/33898871
http://dx.doi.org/10.1016/j.bioactmat.2021.03.027