Cargando…
Study the lipidoid nanoparticle mediated genome editing protein delivery using 3D intestinal tissue model
Lipid nanoparticles are promising carriers for oral drug delivery. For bioactive cargos with intracellular targets, e.g. gene-editing proteins, it is essential for the cargo and carrier to remain complexed after crossing the epithelial layer of intestine in order for the delivery system to transport...
Autores principales: | Yang, Tao, Han, Haobo, Chen, Ying, Yang, Liu, Parker, Rachael, Li, Yamin, Kaplan, David L., Xu, Qiaobing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056182/ https://www.ncbi.nlm.nih.gov/pubmed/33898871 http://dx.doi.org/10.1016/j.bioactmat.2021.03.027 |
Ejemplares similares
-
In situ cancer vaccination using lipidoid nanoparticles
por: Chen, Jinjin, et al.
Publicado: (2021) -
Neurotransmitter-derived lipidoids (NT-lipidoids) for enhanced brain delivery through intravenous injection
por: Ma, Feihe, et al.
Publicado: (2020) -
Immunogenicity Testing of Lipidoids In Vitro and In Silico: Modulating Lipidoid-Mediated TLR4 Activation by Nanoparticle Design
por: de Groot, Anne Marit, et al.
Publicado: (2018) -
Development of Lipidoid Nanoparticles for siRNA Delivery to Neural Cells
por: Khare, Purva, et al.
Publicado: (2021) -
Lipidoid Nanoparticles for siRNA Delivery to the Intestinal Epithelium: In Vitro Investigations in a Caco-2 Model
por: Ball, Rebecca L., et al.
Publicado: (2015)