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Clonally Focused Public and Private T Cells in Resected Brain Tissue From Surgeries to Treat Children With Intractable Seizures

Using a targeted transcriptomics approach, we have analyzed resected brain tissue from a cohort of 53 pediatric epilepsy surgery cases, and have found that there is a spectrum of involvement of both the innate and adaptive immune systems as evidenced by the differential expression of immune-specific...

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Detalles Bibliográficos
Autores principales: Chang, Julia W., Reyes, Samuel D., Faure-Kumar, Emmanuelle, Lam, Sandi K., Lawlor, Michael W., Leventer, Richard J., Lew, Sean M., Lockhart, Paul J., Pope, Kathryn, Weiner, Howard L., Salamon, Noriko, Vinters, Harry V., Mathern, Gary W., Fallah, Aria, Owens, Geoffrey C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056262/
https://www.ncbi.nlm.nih.gov/pubmed/33889159
http://dx.doi.org/10.3389/fimmu.2021.664344