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Sulforaphane exposure impairs contractility and mitochondrial function in three-dimensional engineered heart tissue

Sulforaphane (SFN) is a phytochemical compound extracted from cruciferous plants, like broccoli or cauliflower. Its isothiocyanate group renders SFN reactive, thus allowing post-translational modification of cellular proteins to regulate their function with the potential for biological and therapeut...

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Detalles Bibliográficos
Autores principales: Rhoden, Alexandra, Friedrich, Felix W., Brandt, Theresa, Raabe, Janice, Schweizer, Michaela, Meisterknecht, Jana, Wittig, Ilka, Ulmer, Bärbel M., Klampe, Birgit, Uebeler, June, Piasecki, Angelika, Lorenz, Kristina, Eschenhagen, Thomas, Hansen, Arne, Cuello, Friederike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056268/
https://www.ncbi.nlm.nih.gov/pubmed/33831709
http://dx.doi.org/10.1016/j.redox.2021.101951