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E2F2 stimulates CCR4 expression and activates synovial fibroblast-like cells in rheumatoid arthritis

AIM OF THE STUDY: E2F transcription factor 2 (E2F2) has increased expression in synovial tissues of rheumatoid arthritis (RA) and stimulates interleukin (IL)-1 α and IL-β production in cultured RA synovial fibroblast-like cells (RASF), which supports the importance of E2F2 in RA pathogenesis. This s...

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Detalles Bibliográficos
Autores principales: Xu, Wanju, Li, Shufeng, Chang, Xiaotian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056345/
https://www.ncbi.nlm.nih.gov/pubmed/33897281
http://dx.doi.org/10.5114/ceji.2021.105243