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Diagnostic and therapeutic pitfalls in NPM1-mutated AML: notes from the field

Mutations of Nucleophosmin (NPM1) are the most common genetic abnormalities in adult acute myeloid leukaemia (AML), accounting for about 30% of cases. NPM1-mutated AML has been recognized as distinct entity in the 2017 World Health Organization (WHO) classification of lympho-haematopoietic neoplasms...

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Detalles Bibliográficos
Autores principales: Falini, Brunangelo, Sciabolacci, Sofia, Falini, Lorenza, Brunetti, Lorenzo, Martelli, Maria Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056374/
https://www.ncbi.nlm.nih.gov/pubmed/33879827
http://dx.doi.org/10.1038/s41375-021-01222-4