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Targeting G-quadruplex Forming Sequences with Cas9
[Image: see text] Clustered regularly interspaced palindromic repeats (CRISPR) and CRISPR-associated (Cas) proteins, particularly Cas9, have provided unprecedented control on targeting and editing specific DNA sequences. If the target sequences are prone to folding into noncanonical secondary struct...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056391/ https://www.ncbi.nlm.nih.gov/pubmed/33769784 http://dx.doi.org/10.1021/acschembio.0c00687 |