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Preferentially released miR-122 from cyclodextrin-based star copolymer nanoparticle enhances hepatoma chemotherapy by apoptosis induction and cytotoxics efflux inhibition

Chemotherapy, as one of the most commonly used treatment modalities for cancer therapy, provides limited benefits to hepatoma patients, owing to its inefficient delivery as well as the intrinsic chemo-resistance of hepatoma. Bioinformatic analysis identified the therapeutic role of a liver-specific...

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Detalles Bibliográficos
Autores principales: Xiong, Qingqing, Bai, Yang, Shi, Run, Wang, Jian, Xu, Weiguo, Zhang, Mingming, Song, Tianqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056416/
https://www.ncbi.nlm.nih.gov/pubmed/33898875
http://dx.doi.org/10.1016/j.bioactmat.2021.03.026