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Inhibition of DKC1 induces telomere-related senescence and apoptosis in lung adenocarcinoma

BACKGROUND: Lung cancer is one of the most widely spread cancers in the world and half of the non-small cell lung cancers are lung adenocarcinoma (LUAD). Although there were several drugs been approved for LUAD therapy, a large portion of LUAD still cannot be effectively treated due to lack of avail...

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Detalles Bibliográficos
Autores principales: Kan, Guangyan, Wang, Ziyang, Sheng, Chunjie, Yao, Chen, Mao, Yizhi, Chen, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056518/
https://www.ncbi.nlm.nih.gov/pubmed/33879171
http://dx.doi.org/10.1186/s12967-021-02827-0