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Transcriptomic profiling of three-dimensional cholangiocyte spheroids long term exposed to repetitive Clonorchis sinensis excretory-secretory products

BACKGROUND: Biliary tract infection with the carcinogenic human liver fluke, Clonorchis sinensis, provokes chronic inflammation, epithelial hyperplasia, periductal fibrosis, and even cholangiocarcinoma. Complications are proportional to the intensity and duration of the infection. In addition to mec...

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Detalles Bibliográficos
Autores principales: Kim, Jung-Woong, Yi, Junyeong, Park, Jinhong, Jeong, Ji Hoon, Kim, Jinho, Won, Jihee, Chung, Seok, Kim, Tong-Soo, Pak, Jhang Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056535/
https://www.ncbi.nlm.nih.gov/pubmed/33879231
http://dx.doi.org/10.1186/s13071-021-04717-2