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Novel insights into the m(6)A-RNA methyltransferase METTL3 in cancer

N6-methyladenosine (m(6)A) is a prevalent internal RNA modification in higher eukaryotic cells. As the pivotal m(6)A regulator, RNA methyltransferase-like 3 (METTL3) is responsible for methyl group transfer in the progression of m(6)A modification. This epigenetic regulation contributes to the struc...

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Detalles Bibliográficos
Autores principales: Cai, Yiqing, Feng, Rui, Lu, Tiange, Chen, Xiaomin, Zhou, Xiangxiang, Wang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056546/
https://www.ncbi.nlm.nih.gov/pubmed/33879256
http://dx.doi.org/10.1186/s40364-021-00278-9