A flexible ChIP-sequencing simulation toolkit

BACKGROUND: A major challenge in evaluating quantitative ChIP-seq analyses, such as peak calling and differential binding, is a lack of reliable ground truth data. Accurate simulation of ChIP-seq data can mitigate this challenge, but existing frameworks are either too cumbersome to apply genome-wide...

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Detalles Bibliográficos
Autores principales: Zheng, An, Lamkin, Michael, Qiu, Yutong, Ren, Kevin, Goren, Alon, Gymrek, Melissa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056602/
https://www.ncbi.nlm.nih.gov/pubmed/33879052
http://dx.doi.org/10.1186/s12859-021-04097-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056602/
https://www.ncbi.nlm.nih.gov/pubmed/33879052
http://dx.doi.org/10.1186/s12859-021-04097-5

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