Cargando…
Modeling transcriptional regulation using gene regulatory networks based on multi-omics data sources
BACKGROUND: Transcriptional regulation is complex, requiring multiple cis (local) and trans acting mechanisms working in concert to drive gene expression, with disruption of these processes linked to multiple diseases. Previous computational attempts to understand the influence of regulatory mechani...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056605/ https://www.ncbi.nlm.nih.gov/pubmed/33874910 http://dx.doi.org/10.1186/s12859-021-04126-3 |