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Modeling transcriptional regulation using gene regulatory networks based on multi-omics data sources

BACKGROUND: Transcriptional regulation is complex, requiring multiple cis (local) and trans acting mechanisms working in concert to drive gene expression, with disruption of these processes linked to multiple diseases. Previous computational attempts to understand the influence of regulatory mechani...

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Detalles Bibliográficos
Autores principales:	Patel, Neel, Bush, William S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056605/ https://www.ncbi.nlm.nih.gov/pubmed/33874910 http://dx.doi.org/10.1186/s12859-021-04126-3

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