High-dimensional single cell mass cytometry analysis of the murine hematopoietic system reveals signatures induced by ageing and physiological pathogen challenges

BACKGROUND: Immune ageing is a result of repetitive microbial challenges along with cell intrinsic or systemic changes occurring during ageing. Mice under ‘specific-pathogen-free’ (SPF) conditions are frequently used to assess immune ageing in long-term experiments. However, physiological pathogenic...

Descripción completa

Detalles Bibliográficos
Autores principales: Nikolaou, Christos, Muehle, Kerstin, Schlickeiser, Stephan, Japp, Alberto Sada, Matzmohr, Nadine, Kunkel, Desiree, Frentsch, Marco, Thiel, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056611/
https://www.ncbi.nlm.nih.gov/pubmed/33879187
http://dx.doi.org/10.1186/s12979-021-00230-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056611/
https://www.ncbi.nlm.nih.gov/pubmed/33879187
http://dx.doi.org/10.1186/s12979-021-00230-3

Ejemplares similares