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Lack of the peroxiredoxin 6 gene causes impaired spatial memory and abnormal synaptic plasticity

ABSTRACT: Peroxiredoxin 6 (PRDX6) is expressed dominantly in the astrocytes and exerts either neuroprotective or neurotoxic effects in the brain. Although PRDX6 can modulate several signaling cascades involving cognitive functions, its physiological role in spatial memory has not been investigated y...

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Detalles Bibliográficos
Autores principales: Phasuk, Sarayut, Jasmin, Sureka, Pairojana, Tanita, Chang, Hsueh-Kai, Liang, Kai-Chi, Liu, Ingrid Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056661/
https://www.ncbi.nlm.nih.gov/pubmed/33874992
http://dx.doi.org/10.1186/s13041-021-00779-6