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Monitoring the tacrolimus concentration in peripheral blood mononuclear cells of kidney transplant recipients

AIMS: Tacrolimus is a critical dose drug and to avoid under‐ and overexposure, therapeutic drug monitoring is standard practice. However, rejection and drug‐related toxicity occur despite whole‐blood tacrolimus pre‐dose concentrations ([Tac](blood)) being on target. Monitoring tacrolimus concentrati...

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Detalles Bibliográficos
Autores principales: Francke, Marith I., Hesselink, Dennis A., Li, Yi, Koch, Birgit C.P., de Wit, Lucia E.A., van Schaik, Ron H.N., Yang, Lin, Baan, Carla C., van Gelder, Teun, de Winter, Brenda C.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056738/
https://www.ncbi.nlm.nih.gov/pubmed/33025649
http://dx.doi.org/10.1111/bcp.14585