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Human KIT(+) myeloid cells facilitate visceral metastasis by melanoma
Metastasis of melanoma significantly worsens prognosis; thus, therapeutic interventions that prevent metastasis could improve patient outcomes. Here, we show using humanized mice that colonization of distant visceral organs with melanoma is dependent upon a human CD33(+)CD11b(+)CD117(+) progenitor c...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056753/ https://www.ncbi.nlm.nih.gov/pubmed/33857287 http://dx.doi.org/10.1084/jem.20182163 |