Human KIT(+) myeloid cells facilitate visceral metastasis by melanoma

Metastasis of melanoma significantly worsens prognosis; thus, therapeutic interventions that prevent metastasis could improve patient outcomes. Here, we show using humanized mice that colonization of distant visceral organs with melanoma is dependent upon a human CD33(+)CD11b(+)CD117(+) progenitor c...

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Detalles Bibliográficos
Autores principales: Yu, Chun I., Martinek, Jan, Wu, Te-Chia, Kim, Kyung In, George, Joshy, Ahmadzadeh, Elaheh, Maser, Rick, Marches, Florentina, Metang, Patrick, Authie, Pierre, Oliveira, Vanessa K.P., Wang, Victor G., Chuang, Jeffrey H., Robson, Paul, Banchereau, Jacques, Palucka, Karolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056753/
https://www.ncbi.nlm.nih.gov/pubmed/33857287
http://dx.doi.org/10.1084/jem.20182163

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