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FIT2 organizes lipid droplet biogenesis with ER tubule-forming proteins and septins

Lipid droplets (LDs) are critical for lipid storage and energy metabolism. LDs form in the endoplasmic reticulum (ER). However, the molecular basis for LD biogenesis remains elusive. Here, we show that fat storage–inducing transmembrane protein 2 (FIT2) interacts with ER tubule-forming proteins Rtn4...

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Detalles Bibliográficos
Autores principales: Chen, Fang, Yan, Bing, Ren, Jie, Lyu, Rui, Wu, Yanfang, Guo, Yuting, Li, Dong, Zhang, Hong, Hu, Junjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056755/
https://www.ncbi.nlm.nih.gov/pubmed/33861319
http://dx.doi.org/10.1083/jcb.201907183