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Ucp2-dependent microglia-neuronal coupling controls ventral hippocampal circuit function and anxiety-like behavior

Microglia have been implicated in synapse remodeling by phagocytosis of synaptic elements in the adult brain, but the mechanisms involved in the regulation of this process are ill-defined. By examining microglia-neuronal interaction in the ventral hippocampus, we found a significant reduction in spi...

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Detalles Bibliográficos
Autores principales: Yasumoto, Yuki, Stoiljkovic, Milan, Kim, Jung Dae, Sestan-Pesa, Matija, Gao, Xiao-Bing, Diano, Sabrina, Horvath, Tamas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056795/
https://www.ncbi.nlm.nih.gov/pubmed/33879866
http://dx.doi.org/10.1038/s41380-021-01105-1