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Molecular Design and Synthesis of a Novel Substrate for Assaying Lysozyme Activity

A novel substrate {Galβ1,4GlcNAcβ1,4GlcNAc-β-pNP [Gal(GlcNAc)(2)-β-pNP]} for assaying lysozyme activity has been designed using docking simulations and enzymatic synthesis via β-1,4-galactosyltransferase-mediated transglycosylation from UDP-Gal as the donor to (GlcNAc)(2)-β-pNP as the acceptor. Hydr...

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Detalles Bibliográficos
Autores principales: Matsui, Megumi, Kono, Haruka, Ogata, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Applied Glycoscience 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056892/
https://www.ncbi.nlm.nih.gov/pubmed/34354510
http://dx.doi.org/10.5458/jag.jag.JAG-2018_003