SARS-CoV-2 spike protein dictates syncytium-mediated lymphocyte elimination

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus is highly contagious and causes lymphocytopenia, but the underlying mechanisms are poorly understood. We demonstrate here that heterotypic cell-in-cell structures with lymphocytes inside multinucleate syncytia are prevalent in th...

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Detalles Bibliográficos
Autores principales: Zhang, Zhengrong, Zheng, You, Niu, Zubiao, Zhang, Bo, Wang, Chenxi, Yao, Xiaohong, Peng, Haoran, Franca, Del Nonno, Wang, Yunyun, Zhu, Yichao, Su, Yan, Tang, Meng, Jiang, Xiaoyi, Ren, He, He, Meifang, Wang, Yuqi, Gao, Lihua, Zhao, Ping, Shi, Hanping, Chen, Zhaolie, Wang, Xiaoning, Piacentini, Mauro, Bian, Xiuwu, Melino, Gerry, Liu, Liang, Huang, Hongyan, Sun, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056997/
https://www.ncbi.nlm.nih.gov/pubmed/33879858
http://dx.doi.org/10.1038/s41418-021-00782-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056997/
https://www.ncbi.nlm.nih.gov/pubmed/33879858
http://dx.doi.org/10.1038/s41418-021-00782-3

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