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Mass Cytometry of CSF Identifies an MS-Associated B-cell Population

OBJECTIVE: To identify an MS-specific immune cell population by deep immune phenotyping and relate it to soluble signaling molecules in CSF. METHODS: We analyzed surface expression of 22 markers in paired blood/CSF samples from 39 patients using mass cytometry (cytometry by time of flight). We also...

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Detalles Bibliográficos
Autores principales: Johansson, David, Rauld, Céline, Roux, Julien, Regairaz, Camille, Galli, Edoardo, Callegari, Ilaria, Raad, Layla, Waldt, Annick, Cuttat, Rachel, Roma, Guglielmo, Diebold, Martin, Becher, Burkhard, Kuhle, Jens, Derfuss, Tobias, Carballido, José M., Sanderson, Nicholas S.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057060/
https://www.ncbi.nlm.nih.gov/pubmed/33589541
http://dx.doi.org/10.1212/NXI.0000000000000943