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The newest TRP channelopathy: Gain of function TRPM3 mutations cause epilepsy and intellectual disability
Transient Receptor Potential Melastatin 3 (TRPM3) is a Ca(2+) permeable nonselective cation channel, activated by heat and chemical agonists, such as the endogenous neuro-steroid Pregnenolone Sulfate (PregS) and the chemical compound CIM0216. TRPM3 is expressed in peripheral sensory neurons of the d...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057083/ https://www.ncbi.nlm.nih.gov/pubmed/33853504 http://dx.doi.org/10.1080/19336950.2021.1908781 |