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The newest TRP channelopathy: Gain of function TRPM3 mutations cause epilepsy and intellectual disability

Transient Receptor Potential Melastatin 3 (TRPM3) is a Ca(2+) permeable nonselective cation channel, activated by heat and chemical agonists, such as the endogenous neuro-steroid Pregnenolone Sulfate (PregS) and the chemical compound CIM0216. TRPM3 is expressed in peripheral sensory neurons of the d...

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Detalles Bibliográficos
Autores principales:	Zhao, Siyuan, Rohacs, Tibor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057083/ https://www.ncbi.nlm.nih.gov/pubmed/33853504 http://dx.doi.org/10.1080/19336950.2021.1908781

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