Compensatory effects of M. tuberculosis rpoB mutations outside the rifampicin resistance-determining region

Mycobacterium tuberculosis has been observed to develop resistance to the frontline anti-tuberculosis drug rifampicin, primarily through mutations in the rifampicin resistance-determining region (RRDR) of rpoB. While these mutations have been determined to confer a fitness cost, compensatory mutatio...

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Detalles Bibliográficos
Autores principales: Ma, Pengjiao, Luo, Tao, Ge, Liang, Chen, Zonghai, Wang, Xinyan, Zhao, Rongchuan, Liao, Wei, Bao, Lang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057087/
https://www.ncbi.nlm.nih.gov/pubmed/33775224
http://dx.doi.org/10.1080/22221751.2021.1908096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057087/
https://www.ncbi.nlm.nih.gov/pubmed/33775224
http://dx.doi.org/10.1080/22221751.2021.1908096

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