Cargando…
Compensatory effects of M. tuberculosis rpoB mutations outside the rifampicin resistance-determining region
Mycobacterium tuberculosis has been observed to develop resistance to the frontline anti-tuberculosis drug rifampicin, primarily through mutations in the rifampicin resistance-determining region (RRDR) of rpoB. While these mutations have been determined to confer a fitness cost, compensatory mutatio...
Autores principales: | Ma, Pengjiao, Luo, Tao, Ge, Liang, Chen, Zonghai, Wang, Xinyan, Zhao, Rongchuan, Liao, Wei, Bao, Lang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057087/ https://www.ncbi.nlm.nih.gov/pubmed/33775224 http://dx.doi.org/10.1080/22221751.2021.1908096 |
Ejemplares similares
-
Borderline rpoB mutations transmit at the same rate as common rpoB mutations in a tuberculosis cohort in Bangladesh
por: Lempens, Pauline, et al.
Publicado: (2023) -
The Structural Basis of Mycobacterium tuberculosis RpoB Drug-Resistant Clinical Mutations on Rifampicin Drug Binding
por: Amusengeri, Arnold, et al.
Publicado: (2022) -
Determination of Potentially Novel Compensatory Mutations in rpoC Associated with Rifampin Resistance and rpoB Mutations in Mycobacterium tuberculosis Clinical Isolates from Peru
por: Vargas, Ana Paula, et al.
Publicado: (2020) -
Reevaluating Rifampicin Breakpoint Concentrations for Mycobacterium tuberculosis Isolates with Disputed rpoB Mutations and Discordant Susceptibility Phenotypes
por: Wang, Wei, et al.
Publicado: (2022) -
Rarity of rpoB Mutations Outside the Rifampicin Resistance-Determining Region of Mycobacterium tuberculosis Isolates from Patients Responding Poorly to First-Line Tuberculosis Regimens in Beijing, China: A Retrospective Study
por: Guo, Jidong, et al.
Publicado: (2021)