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Major histocompatibility complex Class II-based therapy for stroke

This review discusses the potential of major histocompatibility complex (MHC) Class II constructs as stroke therapeutics. We focus on the delivery of MHC Class II construct, DRmQ, as a safe and effective treatment for ischemic stroke. DRmQ was observed to attenuate behavioral deficits and decrease m...

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Detalles Bibliográficos
Autores principales: Gonzales-Portillo, Bella M., Lee, Jea-Young, Vandenbark, Arthur A., Offner, Halina, Borlongan, Cesario V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057100/
https://www.ncbi.nlm.nih.gov/pubmed/34084976
http://dx.doi.org/10.4103/bc.bc_16_21