The SARS-CoV-2 mRNA-1273 vaccine elicits more RBD-focused neutralization, but with broader antibody binding within the RBD

The emergence of SARS-CoV-2 variants with mutations in key antibody epitopes has raised concerns that antigenic evolution will erode immunity. The susceptibility of immunity to viral evolution is shaped in part by the breadth of epitopes targeted. Here we compare the specificity of antibodies elicit...

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Detalles Bibliográficos
Autores principales: Greaney, Allison J., Loes, Andrea N., Gentles, Lauren E., Crawford, Katharine H.D., Starr, Tyler N., Malone, Keara D., Chu, Helen Y., Bloom, Jesse D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057239/
https://www.ncbi.nlm.nih.gov/pubmed/33880474
http://dx.doi.org/10.1101/2021.04.14.439844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057239/
https://www.ncbi.nlm.nih.gov/pubmed/33880474
http://dx.doi.org/10.1101/2021.04.14.439844

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