Controlling for cellular heterogeneity using single-cell deconvolution of gene expression reveals novel markers of colorectal tumors exhibiting microsatellite instability

Approximately 15% of colorectal cancer (CRC) cases present with high levels of microsatellite instability (MSI-H). Bulk RNA-sequencing approaches have been employed to elucidate transcriptional differences between MSI-H and microsatellite stable (MSS) CRC tumors. These approaches are frequently conf...

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Detalles Bibliográficos
Autores principales: Devall, Matthew A.M., Casey, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057268/
https://www.ncbi.nlm.nih.gov/pubmed/33889300
http://dx.doi.org/10.18632/oncotarget.27935

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057268/
https://www.ncbi.nlm.nih.gov/pubmed/33889300
http://dx.doi.org/10.18632/oncotarget.27935

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