Carcinoma cells that have undergone an epithelial-mesenchymal transition differentiate into endothelial cells and contribute to tumor growth

Hypoxia stimulates neoangiogenesis, promoting tumor outgrowth, and triggers the epithelial-mesenchymal transition (EMT), which bestows cells with mesenchymal traits and multi-lineage differentiation potential. Here, we investigated whether EMT can confer endothelial attributes upon carcinoma cells,...

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Detalles Bibliográficos
Autores principales: Sphyris, Nathalie, King, Cody, Hoar, Jonathan, Werden, Steven J., Vijay, Geraldine V., Miura, Naoyuki, Gaharwar, Akhilesh, Sarkar, Tapasree Roy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057273/
https://www.ncbi.nlm.nih.gov/pubmed/33889304
http://dx.doi.org/10.18632/oncotarget.27940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057273/
https://www.ncbi.nlm.nih.gov/pubmed/33889304
http://dx.doi.org/10.18632/oncotarget.27940

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