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Carcinoma cells that have undergone an epithelial-mesenchymal transition differentiate into endothelial cells and contribute to tumor growth
Hypoxia stimulates neoangiogenesis, promoting tumor outgrowth, and triggers the epithelial-mesenchymal transition (EMT), which bestows cells with mesenchymal traits and multi-lineage differentiation potential. Here, we investigated whether EMT can confer endothelial attributes upon carcinoma cells,...
Autores principales: | Sphyris, Nathalie, King, Cody, Hoar, Jonathan, Werden, Steven J., Vijay, Geraldine V., Miura, Naoyuki, Gaharwar, Akhilesh, Sarkar, Tapasree Roy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057273/ https://www.ncbi.nlm.nih.gov/pubmed/33889304 http://dx.doi.org/10.18632/oncotarget.27940 |
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