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Loss of CPAP causes sustained EGFR signaling and epithelial-mesenchymal transition in oral cancer

Higher epidermal growth factor receptor (EGFR) signaling can contribute to tumor metastasis and resistance to therapies in oral squamous cell carcinoma (OSCC). EGFR signaling can promote epithelial-mesenchymal transition (EMT) in OSCC. EMT is a process by which epithelial cells acquire invasive prop...

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Detalles Bibliográficos
Autores principales: Gudi, Radhika R., Janakiraman, Harinarayanan, Howe, Philip H., Palanisamy, Viswanathan, Vasu, Chenthamarakshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057274/
https://www.ncbi.nlm.nih.gov/pubmed/33889303
http://dx.doi.org/10.18632/oncotarget.27932