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DP1 prostanoid receptor activation increases the severity of an acute lower respiratory viral infection in mice via TNF-α-induced immunopathology

Respiratory syncytial virus (RSV) bronchiolitis is a leading cause of infant hospitalization and mortality. We previously identified that prostaglandin D2 (PGD2), released following RSV infection of primary human airway epithelial cells or pneumonia virus of mice (PVM) infection of neonatal mice, el...

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Detalles Bibliográficos
Autores principales: Ullah, Md Ashik, Rittchen, Sonja, Li, Jia, Hasnain, Sumaira Z., Phipps, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057290/
https://www.ncbi.nlm.nih.gov/pubmed/33879829
http://dx.doi.org/10.1038/s41385-021-00405-7