Shear and Integrin Outside-In Signaling Activate NADPH-Oxidase 2 to Promote Platelet Activation

OBJECTIVE: Despite the importance of reactive oxygen species (ROS) and NOX (nicotinamide adenine dinucleotide phosphate [NADPH] oxidase) 2 in platelet activation and in vivo thrombosis, it is unclear how ROS and NOX2 play a role in platelet activation and why NOX2 deficiencies in humans and mice do...

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Detalles Bibliográficos
Autores principales: Xu, Zheng, Liang, Ying, Delaney, M. Keegan, Zhang, Yaping, Kim, Kyungho, Li, Jing, Bai, Yanyan, Cho, Jaehyung, Ushio-Fukai, Masuko, Cheng, Ni, Du, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Basic Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057529/
https://www.ncbi.nlm.nih.gov/pubmed/33691478
http://dx.doi.org/10.1161/ATVBAHA.120.315773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057529/
https://www.ncbi.nlm.nih.gov/pubmed/33691478
http://dx.doi.org/10.1161/ATVBAHA.120.315773

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