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Temporal dynamics of a CSF1R signaling gene regulatory network involved in epilepsy

Colony Stimulating Factor 1 Receptor (CSF1R) is a potential target for anti-epileptic drugs. However, inhibition of CSF1R is not well tolerated by patients, thereby prompting the need for alternative targets. To develop a framework for identification of such alternatives, we here develop a mathemati...

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Detalles Bibliográficos
Autores principales: Gérard, Claude, De Mot, Laurane, Cordi, Sabine, van Eyll, Jonathan, Lemaigre, Frédéric P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057615/
https://www.ncbi.nlm.nih.gov/pubmed/33819288
http://dx.doi.org/10.1371/journal.pcbi.1008854