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Syntaxins 6 and 8 facilitate tau into secretory pathways

Tau pathology initiates in defined brain regions and is known to spread along neuronal connections as symptoms progress in Alzheimer's disease (AD) and other tauopathies. This spread requires the release of tau from donor cells, but the underlying molecular mechanisms remained unknown. Here, we...

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Detalles Bibliográficos
Autores principales: Lee, Wei Siang, Tan, Daniel CS, Deng, Yuanyuan, vanHummel, Annika, Ippati, Stefania, Stevens, Claire, Carmona-Mora, Paulina, Ariawan, Daryl, Hou, Liming, Stefen, Holly, Tomanic, Tamara, Bi, Mian, Tomasetig, Florence, Martin, Adam, Fath, Thomas, Palmer, Stephen, Ke, Yazi D., Ittner, Lars M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057678/
https://www.ncbi.nlm.nih.gov/pubmed/33769438
http://dx.doi.org/10.1042/BCJ20200664