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Syntaxins 6 and 8 facilitate tau into secretory pathways
Tau pathology initiates in defined brain regions and is known to spread along neuronal connections as symptoms progress in Alzheimer's disease (AD) and other tauopathies. This spread requires the release of tau from donor cells, but the underlying molecular mechanisms remained unknown. Here, we...
Autores principales: | Lee, Wei Siang, Tan, Daniel CS, Deng, Yuanyuan, vanHummel, Annika, Ippati, Stefania, Stevens, Claire, Carmona-Mora, Paulina, Ariawan, Daryl, Hou, Liming, Stefen, Holly, Tomanic, Tamara, Bi, Mian, Tomasetig, Florence, Martin, Adam, Fath, Thomas, Palmer, Stephen, Ke, Yazi D., Ittner, Lars M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057678/ https://www.ncbi.nlm.nih.gov/pubmed/33769438 http://dx.doi.org/10.1042/BCJ20200664 |
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