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Determination of Voriconazole Plasma Concentration by HPLC Technique and Evaluating Its Association with Clinical Outcome and Adverse Effects in Patients with Invasive Aspergillosis

PURPOSE: Invasive aspergillosis is a prevalent fungal disease, especially in Asian countries with a high mortality rate. Voriconazole (VRZ) is the first choice for invasive aspergillosis treatment. Plasma concentration of this drug is unpredictable and varies among individuals. This variability is i...

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Detalles Bibliográficos
Autores principales: Yousefian, Sahar, Dastan, Farzaneh, Marjani, Majid, Tabarsi, Payam, Barati, Saghar, Shahsavari, Nahid, Kobarfard, Farzad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057903/
https://www.ncbi.nlm.nih.gov/pubmed/33953804
http://dx.doi.org/10.1155/2021/5497427